What is THC-O?

What is THC-O?

The Cannabis industry with its possible consumers in awe of the THC blends may find it exclusively new to discover another ‘THC-O’ with its unique effects. The U.S. DEA first discovered that THC-O was a subdued entity analogue of THC in 1978. Its legality refers to it as a Class-A drug in the U.K. So it is considered as an analogue of THC, in which case purchase, sale, or ownership could be litigated according to the Federal Analog Act in the United States.

This blog feature from HerbzDepot will let you know what is THC-O, known also as THC-O-Acetate.

Why is this synthetic cannabinoid suddenly in the news?

THC-O is a synthetic cannabinoid (3x times more psychoactive than Delta-9), which means you can’t get concentrated doses of pure delta 8 or delta 9 by extracting the chemical from the cannabis plant. THC-O, like all THC molecules, is psychoactive, as you may have guessed. On the other hand, THC-O is not mellow in the same way as delta 8 and delta 10 are.

The importance of THC-O in the marketplace is enormous as the cannabinoids and their assortment are another symposium for CBD professionals and likely customers looking for stronger by-products.

When THC-O ventured into the vicinity, a ripple in the CBD-led market was dented by the upswing of this refined commodity. 

As a result of which, there happens to be a big fuss across the trade of CBD products associated with acetate.

As raw and rare the product may be, the fervour for it is likely to legislate the world of CBD rather than statements that are viewed from across the world at large. Whatever the quest might be, knowing the product and its roots and its efficiency and stature in all respects come about to be one of the most serious cravings in the present-day CBD world.

Owing to the definition, THC-O-Acetate, which got its wings from the parent THC compound stirred fascination for both the call and demand for a new wave of a substitute. Its evolution as a chemical compound as well as product is notable, which holds remarkable value in the health sector. Here is how the product is prepared from THC.

How is THCA converted to THC-O?

  • THC-O for its formation undergoes a complicated chemical process where the carboxylic acid group is hydrolyzed by heating with the sulfuric acid thereby formulating a reaction with excess anhydride acetic acid. It then reacts with regular THC at the hydroxyl group and evolves as the potent THC-O-Acetate.
  • After the reaction takes place, the polar C-OH becomes saviour2C =O-CH3. A trained laboratory establishment is required to manufacture THC-O. The conversion process should be handled by experienced hands. Futile attempts of experimenting without a proper setting by an amateur can lead them to hazardous situations.

Do you know that THC-O is more potent than THC?

According to Donald A. Cooper of DEA “The effect of the acetate is more spiritual and psychedelic than that of the ordinary product. The most unique property of this miraculous compound is that there is a delay of about thirty minutes before its effects are felt.”

  • THC-O is a prodrug of THC which means that it requires it to be deacetylated by enzymes in our bodies before the THC comes to be effective enough for us to feel the reactions.
  • In his publication called Marijuana Chemistry: Genetics, Processing, Potency Michael Stark asserted that the covert THC-O was 300 percent harder than the psychoactive THC we have known.
  • Despite the use of THC, at times, we may not be satisfied with its ability for providing relief. Then, comes the supreme savior with potential that is reportedly 30 times more than that of THC. The surge for stronger cannabinoids has been naturally rising in recent times and it’s no wonder if anyone switches to THC-O.

5 interesting facts about THC-O

  • The THC acetate ester is the acetate ester of THC, a manufactured cannabinoid that can only be produced in a lab.
  • This compound is high in its purity as a milligram of isolate equals exactly a milligram of cannabinoid.
  • The acetylation of THC does not alter the properties of the blend to a similar as with other acetate estanaloguesnce the parent compound (THC) is already lipophilic regardless of its enhanced efficacy.
  • It is significant as it occurs to be one of the few analogues of THC to have been discovered as a recreational drug traded and consumed in a highly smokable form.
  • If aided by an effective analytical standard for testing the manufacturers can procure them in the market anytime soon.

Furthermore, the recreational uses of such products can be higher than what we are expecting. As mentioned earlier, for those who are in search of stronger cannabinoids, this could be a rewarding choice. People who have given it a shot are likely to deem it better than regular THC.

Future prospects

It was then when the U.S. military started to begin to conduct experiments using THC-O as a weapon for hamstringing agents for warfare. Reportedly, in an instance, this version of THC had also been used to impair the muscles of dogs with twice the strength of regular THC. In the U.S. the compound isn’t listed as a scheduled drug, nevertheless, in 1986 it had made the analogs of THC illegal. 

Both the U.S. and the New Zealand governments witnessed certain cases of THC-O in 1995 and are known to outlaw them. If manufactured with correctness this cannabinoid has to have properties such as water solubility which makes it possible to add it to many products. Besides, it could be used as a chemical alternative where natural cannabinoid does not work. This synthetic cannabinoid may haggle with those patients who need a stronger dose for the possibility of easier some symptoms.


Delta-8 FAQs

Despite the odds, cannabis, CBD, and THC-O products are rampantly invading the market, leaving customers pleased, content, and in awe of it. Stores after stores in the market are filling up with new CBD and THC products, which, according to numerous scientific studies and research, are impacting millions of lives around the world, starting from the US and Canada.

THC-O Acetate Vape Cartridges are a new evolving phenomenon in the latest craze where Herbz Depot is playing a crucial role to deliver high-quality THC-O cartridges right to your doorstep. As many folks are still unaware of the vast scope of CBD and THC-O, this FAQ section will certainly help to enhance awareness of the products related to the incredible compounds that may soon reshape the healthcare industry.

What are THC-O and THC-O Cartridge?

Tetrahydrocannabinol acetate is abbreviated as THC-O (or THC-O acetate). It’s a synthetic version of delta-9 THC. It is one among many other cannabinoids found in hemp and cannabis variant plants. Although THC-O can be extracted directly from cannabis and hemp plants, the Acetate extraction amount will be quite less, which means you can’t get a good amount of THC-O Acetate if you extract directly from the plants. Hence, experts rely on another synthetic process to increase the yield. THC (delta 8 or delta 9) or THCA are acetylated to produce THC-O Acetate and its supplements like vape cartridges. 

Acetylation is a chemical reaction in which an acetyl group (CH3C=O) replaces a hydrogen group.

The final extraction is poured into a container for vaping application, which is termed as THC-O Cartridge, and which is literally gaining widespread acclamation from both users and the scientific community.

Why should you use THC-O Vape Cartridges?

THC-O is widely accepted to play a key role in suppressing numerous mental conditions and chronic pain. Other benefits of THC-O or THC-O cartridges

  1. It may help to alleviate pain for trauma and accident-related cases
  2. THC-O has the ability to fight inflammation inside the body
  3. THC-O compound might help to relax and make things soothing and comfortable even when you are under terrible stress
  4. THC-O can be highly beneficial for people suffering from depression, anxiety, social fear (social anxiety disorder), and bipolar disorders
  5. THC-O also may help to increase appetite by enhancing metabolic activities, thereby also participates in reducing body weight
  6. THC-O can be also useful to bring considerable effect against insomnia or sleeplessness.

What is the difference between THC-O and Delta THC?

Basically, all forms of THC are termed cannabinoids that are organic compounds extracted directly or indirectly from hemp and cannabis plants. 

Delta-9 or Delta-8 THC was quite popular in the market before THC-O came into the picture. 

The main difference between THC-O and other forms of THC is that of their structure and effects on the mind and body.

THC-O is a synthetic compound of Delta-9 THC but it is 300% more potent than all the known THC compounds. Moreover, THC-O cartridges, when vaped, can start to show effect faster than other THC.

Does THC-O Vape Cartridges give side effects?

THC-O cartridge is widely used in the US and Canada ever since the news came up regarding its miraculous features and performance but as it is a chemical compound, hence, certain side effects may be there.

However, these side effects are not long-term as they tend to fade away once the body becomes compatible with the compound or vape cartridge oil.

Common side effects may include dizziness, impatience, muscle cramps, memory loss, dry mouth, red eyes, etc.

What is the best way to consume THC-O?

According to some evidence, THC-O Acetate may act as a prodrug when taken orally, meaning it could convert to Delta-9 in the liver. However, no one is certain as studies are still limited in this field.

Hence, vaping THC-O oil is the best process to consume THC-O Acetate. Vaping is popular for fast effects as the compound gets to interact quickly with the endocannabinoid receptors of the body. 

If you are looking to order THC-O in North Carolina, you can get the best THC-O oil with vape cartridges from Herbz Depot at affordable pricing.

Why Herbz Depot’s THC-O might be counted as the best in the market?

Herbz Depot’s THC-O Acetate supplements don’t carry the unpleasant organic smell as they are blended with superior cannabis terpenes, flavour, distilled water, etc. Moreover, buying THC-O Acetate from branded enterprises can lead to satisfactory customer experience, cost-effective scenarios, and reputation, which will subsequently raise the stake of your business.

Smoking vape cartridges of THC-O are known to offer instant high and relief against mental conditions within 15-20 minutes.

What is the minimum age limit to order THC-O in North Carolina?

THC-O for sale literally means to any state but not kids and teenagers below 18. To order THC-O in North Carolina, you must be at least 18 years old. While there are no federal regulations dictating the minimum age for purchasing THC-O, several state regulations stipulate that buyers must be at least 21 years old. As a result, to purchase any products online or in-store, you must be 21 years old or older.

Can I start a new business with THC-O products like vape cartridges?

Yes, definitely. Herbz Depot offers THC-O for sale along with various kinds of wholesale distribution services for both local and international THC-O and CBD products. 

Herbz Depot is also well-known for packaging and labelling services, which can help you to sell your products faster to your customers. Our white and private labelling services along with robust packaging solutions can help you to speed up the business process without worrying about distribution and packaging issues.

States, which allow THC-O Vape Cartridges legally?

Typically, companies send products to 38 of the 50 states in the United States: Alabama, California, Colorado, Connecticut, Florida, Georgia, Hawaii, Illinois, Indiana, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Missouri, Nebraska, New Hampshire, New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, South Carolina, South Dakota, Tennessee, Texas, Vermont, Virginia, Washington, West Virginia, Wisconsin, Wyoming.

If you want to buy or order THC-O in North Carolina, the Herbz Depot has plenty of exciting offers to fulfill your needs.

Unfortunately, companies cannot currently ship to Alaska, Arizona, Arkansas, California, Colorado, Delaware, Idaho, Iowa, Mississippi, Montana, Nebraska, Nevada, or Utah due to the lack of favourable Hemp or CBD laws in twelve states.


We cannot deny the fact that the sense of spirituality, psychedelic, and introspection go loftier with the version than the usual THC thereby, explaining the variation that comes about with a little molecular disparity amongst the users. 

But, for now, we are also obliged to stick to a credible source from the market. There is a lot of exposure in providing and receiving online services in the present times, which carries a chance of illegal supply along with free supply. It would be safer for the consumers to take note of the leads they have when shopping for these products online or offline. 

As new compounds like THC-O tend to arrive in the market the eagerness for the utility of the product bears the chance to remain at the peak. But why is it that this decade-old friend still lives in disguise? Have we been able to assess the pros and cons of this Acetate? These questions raise speculations amongst the public and the governance and the global village still awaits an answer.

Though the product and its chemistry with the receptors could be a temptation we shouldn’t forget to comply with the law of the land as well as ensure to ourselves that our basic needs are being fulfilled fairly keeping in mind our biological needs and adaptation.


  1. Information about “THC-O-acetate” on Wikipedia
  2. Cannabis Tech article “THCO-Acetate: A Quest in Cannabinoid Chemistry”
  3. Honest Marijuana article “THC-O-Acetate: What It Is And What You Need To Know About It”
  4. En-academic article “THCO-acetate”
  5. Daily CBD article “THCO: The Psychedelic Cannabinoid”